Thesis Advisor
Entering Year
Research: Resident memory T cells (TDrM) are confined to individual non-lymphoid tissues, where they survey their local environment for cognate antigen. I investigate the mechanisms dictating TDrM establishment, maintenance, and function, specifically focusing on how these factors change as organisms age. For example, TDrM have traditionally been considered terminally differentiated, but recent reports demonstrate that, following acute infection, some TDrM exit their host tissue and rejoin the circulating T cell compartment. Part of my thesis research assesses the prevalence, tissue ontogeny, and function of these “ex-TDrM.”
